Reductive amination of acetals by anilines in the presence of triethylsilane and iodine

XL Zhang, P Yu, YW Wu, QP Wu…

Index: Zhang, Xue-Lin; Yu, Pan; Wu, Yong-Wei; Wu, Qin-Pei; Zhang, Qing-Shan Journal of Chemical Research, 2014 , vol. 38, # 5 p. 261 - 264

Full Text: HTML

Citation Number: 0

Abstract

A mild and efficient method for N-alkylation of aromatic amines with various acetals such as aryl, alkyl, cyclic and acyclic acetals was developed. A number of aromatic amines bearing electron-donating or electron-withdrawing substituents were directly alkylated by acetals with excellent yields. The method uses a catalytic amount of I2 and triethylsilane as the hydride source without a metal present. Monoalkylation with excellent chemoselectivity ...

Related Articles:

Preparation of N-arylamines from 2-oxo-7-azobicyclo [4.1. 0] heptanes

[Barros, M. Teresa; Dey, Suvendu S.; Maycock, Christopher D.; Rodrigues, Paula Tetrahedron, 2012 , vol. 68, # 31 p. 6263 - 6268]

Enantioselective synthesis and enhanced circularly polarized luminescence of S-shaped double azahelicenes

[Zhang, Yu; Yang, Xinye; Yao, Qizheng; Ma, Dawei Organic Letters, 2012 , vol. 14, # 12 p. 3056 - 3059]

Recyclable palladium catalyst for facile synthesis of imines from benzyl alcohols and nitroarenes

[Chen, Jing; Huang, Shijun; Lin, Jin; Su, Weiping Applied Catalysis A: General, 2014 , vol. 470, p. 1 - 7]

Selective N??Alkylation of Amines with Alcohols by Using Non??Metal??Based Acid–Base Cooperative Catalysis

[Du, Ya; Oishi, Shunsuke; Saito, Susumu Chemistry - A European Journal, 2011 , vol. 17, # 44 p. 12262 - 12267]

Direct One??Pot Reductive N??Alkylation of Nitroarenes by using Alcohols with Supported Gold Catalysts

[Tang, Chun-Hong; He, Lin; Liu, Yong-Mei; Cao, Yong; He, He-Yong; Fan, Kang-Nian Chemistry - A European Journal, 2011 , vol. 17, # 26 p. 7172 - 7177]

More Articles...