Direct and Diastereoselective Alkylation and Aldol Reactions of α-Bromo-α-fluoro-β-lactams
…, T Kawakita, K Sato, M Omote…
Index: Bateson, John H.; Quinn, Alison M.; Smale, Terence C.; Southgate, Robert Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 2219 - 2234
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Citation Number: 7
Abstract
... 8, Bn, 4-FC 6 H 4, 3g, 7g, 81. a ... The lithiation of 3e was carried out at −100 °C. ... with strong NOE correlations observed between the protons at the C3 and C4 positions in the (3R,4S)/(3S,4R)- isomer 5. All of the (3R,4S)/(3S,4R)-isomer products possessed a small hydrogen–fluorine ...
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