Chinese Chemical Letters

A total synthesis of mycalisine A

YH Dou, HX Ding, RC Yang, W Li, Q Xiao

Index: Dou, Yan-Hui; Ding, Hai-Xin; Yang, Ru-Chun; Li, Wei; Xiao, Qiang Chinese Chemical Letters, 2013 , vol. 24, # 5 p. 379 - 382

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Citation Number: 3

Abstract

In this paper, we report a total synthesis of a naturally occurring pyrrolo [2, 3-d] pyrimidine nucleoside, mycalisine A. Our synthetic strategy uses d-xylose as the starting material and Vorbrüggen glycosylation as the key step. Mycalisine A was synthesized in 11 steps with a 15% overall yield.