The Journal of Organic Chemistry

Folate analogs. 19. Construction of some 6-substituted 7, 8-dihydro-8-thiopterins

MG Nair, LH Boyce, M Berry

Index: Nair, M.G.; Boyce, Loretta H.; Berry, Michael A. Journal of Organic Chemistry, 1981 , vol. 46, # 16 p. 3354 - 3357

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Citation Number: 7

Abstract

Although three 6-aryl-substituted 7, 8-dihydro-8-thiopterins' were recently described in the literature4 and were found to be relatively stable, no corresponding data are available on the desired 6-alkyl-substituted 7, gdihydro-8-thiopterins. The stability and spectral characteristics of the 6-alkyl-and 6-aryl-substituted 7, 8-dihydro-8-thiopterins are expected to differ considerably due to the presence of extended conjugation in the structure of the ...