Procedure for the conversion of 1-alkynes into alkylcyclopropanes and trans-1-halo-2-alkylcyclopropanes via the hydroalumination reaction

G Zweifel, GM Clark, CC Whitney

Index: Zweifel,G. et al. Journal of the American Chemical Society, 1971 , vol. 93, p. 1305 - 1307

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Citation Number: 26

Abstract

A representative example of the procedure for the preparation of alkylcyclopropanes from l- alkynes is as follows. To 75 mmol of l-hexyne in 15 ml of n-hexane was added 75 mmol of diisobutylaluminum hydride, while maintaining the temperature during the addition at 25- 30". The solution was stirred at ambient temperature for 30 min, then heated at 50" for 4 hr. After cooling the mixture to room temperature, the solvent was removed under reduced ...

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