RESEARCHES ON HYDANTOINS. XLIII. SYNTHESIS OF THE POLYPEPTIDE-HYDANTOIN:“HYDANTOIN-3-ACETIC ACID” 1

TB Johnson, AG Renfrew

Index: Johnson; Renfrew Journal of the American Chemical Society, 1925 , vol. 47, p. 244

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Citation Number: 8

Abstract

Of the three hydantoin-acetic acids theoretically possible two have already been described in the literature, namely, hydantoin-5-acetic acid3 I11 (“malyureidsaure”), and hydantoin-1- acetic acid4 I. In this paper we shall describe a method of preparing the third representative of this series, namely, hydantoin-3-acetic acid 11. This compound is of immediate biological interest as it is the simplest representative of the NH-CO HOOCCHzN-CO NII-CO

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