Cobalt (II)??Catalyzed Isocyanide Insertion Reaction with Amines under Ultrasonic Conditions: A Divergent Synthesis of Ureas, Thioureas and Azaheterocycles

…, XP Xu, JJ Cao, TQ Wei, SY Wang…

Index: Zhu, Tong-Hao; Xu, Xiao-Ping; Cao, Jia-Jia; Wei, Tian-Qi; Wang, Shun-Yi; Ji, Shun-Jun Advanced Synthesis and Catalysis, 2014 , vol. 356, # 2-3 p. 509 - 518

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Citation Number: 23

Abstract

Abstract: Cobalt (II) acetylacetonate-catalyzed isocyaACHTUNGTRENNUNGnide insertion reactions with amines utilizing tert-butyl hydroperoxide (TBHP) as an oxidant under ultrasound conditions have been developed, which lead to the synthesis of ureas, thioureas, as well as 2-aminobenzimidazoles, 2-aminobenzothiazoles, and 2-aminobenzoxazoles under the general reaction conditions in up to 96% yields, respectively. The intermediate ...