The Journal of Organic Chemistry

Reagents for bioorganic synthesis. 2. Methyl N-(dicarbomethoxymethyl) methanimidate

BB Lim, RS Hosmane

Index: Lim, Benjamin B.; Hosmane, Ramachandra S. Journal of Organic Chemistry, 1985 , vol. 50, # 25 p. 5111 - 5115

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Citation Number: 11

Abstract

Preparation, properties, and reactions of the reagent methyl N-(dicarbomethoxymethy1) methanimidate (1) are reported. Dropwise addition of dimethyl aminomalonate to refluxing trimethyl orthoformate/TFA afforded 1. Treatment of 1 with ammonia and various primary