Synthetic Communications

Synthetic Reactions by Complex Catalysts. XXII. Copper-Catalyzed Reaction of Isonitrile with Active Methylene Compounds

T Saegusa, I Murase, Y Ito

Index: Saegusa,T. et al. Synthetic Communications, 1971 , vol. 1, p. 145 - 152

Full Text: HTML

Citation Number: 3

Abstract

Abstract In previous papers2–6) we have reported the copper catalyzed reactions of isonitrile with various RQH compounds, in which the terminal carbon atom of isonitrile is inserted between heteroatom-hydrogen bonds, ie, NH bond of amine, PH of phosphine, OH of alcohol, SH of thiol and Si-H of silane,(eq. 1). In these reactions, the derivatives of hypothetical “fonirnidfc acid”, HC ([dbnd] NR) OH, are produced in high yields. These ...

Related Articles:

Convenient preparation of functionalised polymer-based resins via an economical preparation of chloromethylated polystyrene resins (Merrifield Type)

[Le Carre, Erica; Lewis, Norman; Ribas, Christina; Wells, Andrew Organic Process Research and Development, 2000 , vol. 4, # 6 p. 606 - 610]

Solvent-free synthesis of quinolone derivatives

[Cernuchova, Petra; Vo-Thanh, Giang; Milata, Viktor; Loupy, Andre Heterocycles, 2004 , vol. 64, p. 177 - 191]

CONVENIENT GENERAL SYNTHESIS OF ALPHA-AMINOLUNSATURATED KETONES, NITRILESAND THEIR USE IN NENITZESCUE INDOLE SYNTHESIS

[Mayadeo, M. S.; Gandhi, S. A. Journal of the Indian Chemical Society, 1994 , vol. 71, # 5 p. 281 - 282]

More Articles...