Tetrahedron

Nuclbophilic substitution reactions of the heterocyclic fluoro-olefin perfluoro-(3, 6-dihydro-2-methyl-2H-1, 2-oxazine)

PA Carson, DW Roberts

Index: Carson, P. A.; Roberts, D. W. Tetrahedron, 1986 , vol. 42, # 23 p. 6495 - 6510

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Citation Number: 4

Abstract

Perfluoro-(3, 6-dihydro-2-methyl-2H-l, 2-oxazine) reacts with nucleophlles to produce mixtures of the 4-aad 5-subitltuted derivatives, with the latter in preponderance. Neither double bond isomerisation nor allyllc subititution are observed. Bistrifluoromethylnitroxide adds quantitatively to the olefinic bond of the parent oxazine. Perfluoro (3, 6-dihydro-2- methyl-2H-l, 2-oxazine) exhibits a high thermal and photolytic stability. This, together with ...