N-Tosyloxycarbamates as a source of metal nitrenes: rhodium-catalyzed CH insertion and aziridination reactions

H Lebel, K Huard, S Lectard

Index: Lebel, Helene; Huard, Kim; Lectard, Sylvain Journal of the American Chemical Society, 2005 , vol. 127, # 41 p. 14198 - 14199

Full Text: HTML

Citation Number: 182

Abstract

The rhodium-catalyzed decomposition of N-tosyloxycarbamates to generate metal nitrenes which undergo intramolecular CH insertion or aziridination reaction is described. Aliphatic N- tosyloxycarbamates produce oxazolidinones with high yields and stereospecificity through insertion in benzylic, tertiary, and secondary CH bonds. Intramolecular aziridination occurs with allylic N-tosyloxycarbamates to produce aziridines as single diastereomers. The ...

Related Articles:

Zur cyclisierenden Carbonylierung von 3??Hydroxycarbohydroxamsäuren mit 1, 1′??Carbonyldiimidazol1a)

[Geffken, Detlef Liebigs Annalen der Chemie, 1982 , # 2 p. 219 - 225]

New Reactions Involving Alkaline Treatment of 3-Nitroso-2-oxazolidones. II

[Newman; Edwards Journal of the American Chemical Society, 1954 , vol. 76, p. 1840,1842]

New Reactions Involving Alkaline Treatment of 3-Nitroso-2-oxazolidones. II

[Newman; Edwards Journal of the American Chemical Society, 1954 , vol. 76, p. 1840,1842]

New Reactions Involving Alkaline Treatment of 3-Nitroso-2-oxazolidones. II

[Newman; Edwards Journal of the American Chemical Society, 1954 , vol. 76, p. 1840,1842]

More Articles...