Potential antiinflammatory agents. Aralkoxyhydrouracils and aralkoxyhydantoins

L Simet, DB Reisner, BJ Ludwig…

Index: Simet,L. et al. Journal of Medicinal Chemistry, 1970 , vol. 13, p. 1067 - 1071

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Citation Number: 2

Abstract

(4) See 1). J. Brown," The Pyrimidines," Interscience, New York, SP, 1962, pp 434-436, for a discussion. boxylation, or bj. reduction of an enamine of a P-lieto ester. Holyever, when R1 is aralkoxy, we found that only benzyloxyamine and a fen ring-substituted benzyloxyamines could be added to ethyl acrylate and these amines failed to add to methyl methacrylate. The aminomethylation reaction and enamine reduction also failed to yield the esters needed ...