Angewandte Chemie International Edition

Iridium??Catalyzed Asymmetric Hydrogenation of α??Alkylidene Succinimides

Y Liu, W Zhang

Index: Liu, Xu; Han, Zhaobin; Wang, Zheng; Ding, Kuiling Angewandte Chemie - International Edition, 2014 , vol. 53, # 7 p. 1978 - 1982 Angew. Chem., 2014 , vol. 126, # 7 p. 2009 - 2013,5

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Citation Number: 24

Abstract

Enantiopure succinimide derivatives are key structures in biologically active natural products, pharmaceuticals, and important intermediates in organic synthesis.[1, 2] Compounds containing a chiral pyrrolidine motif, which display activity in many biological systems, can be obtained from succinimide derivatives by simple transformations.[3] However, few methodologies exist concerning the synthesis of chiral succinimide ...

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