Microwave-Assisted Multicomponent Synthesis of Aza-, Diaza-, Benzo-, and Dibenzofluorenedione Derivatives

A Defant, G Guella, I Mancini

Index: Defant, Andrea; Guella, Graziano; Mancini, Ines Synthetic Communications, 2008 , vol. 38, # 17 p. 3003 - 3016

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Citation Number: 9

Abstract

Abstract A microwave procedure was efficiently applied to the synthesis of a series of heteropolycyclic compounds with known or potential biological activities. Antitumor amide 3 was obtained in a few minutes and with high yields through a solventless, one-pot cyclization, followed by treatment with the suitable amine. This method was also used to access tetracyclic aza-compounds 5/6, where their selective formation as N, N-syn and N, ...