Journal of the American Chemical Society

Complexation of benzamidinium by a new family of artificial receptors

TW Bell, VJ Santora

Index: Bell, Thomas W.; Santora, Vincent J. Journal of the American Chemical Society, 1992 , vol. 114, # 21 p. 8300 - 8302

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Citation Number: 17

Abstract

Figure 1. Synthesis of benzamidine receptors 1 and 2:(a) Et, N, CH, CN, reflux (66%);(b) H2NNH2, EtOH, reflux/HCI (86%);(c) 6, in a number of important antibacterial and antiprotozoal agents4 We are particularly interested in developing a synthetic receptor capable of recognizing pentamidine isethionate (3), an important DNA-binding bis (benzamidine) drug used for treatment of Pneumocystis carinii in AIDS patient^.^ In this ...