Polymer

Synthesis and characterization of bioactive molecules grafted on poly (ɛ-caprolactone) by “click” chemistry

J Suksiriworapong, K Sripha, VB Junyaprasert

Index: Suksiriworapong, Jiraphong; Sripha, Kittisak; Junyaprasert, Varaporn Buraphacheep Polymer, 2010 , vol. 51, # 11 p. 2286 - 2295

Full Text: HTML

Citation Number: 23

Abstract

A facile and efficient strategy to graft bioactive molecules (nicotinic acid, p-aminobenzoic acid, and phthaloyltryptophan) onto poly (ɛ-caprolactone)(P (ɛCL)) was achieved by copper- catalyzed Huisgen's 1, 3-dipolar cycloaddition known as click reaction. P (αClɛCL), with 10, 20, and 30% of α-chloro-ɛ-caprolactone (αClɛCL) units were copolymerized by ring opening polymerization using ɛCL and αClɛCL as starting materials in the presence of 1, ...