Study for the determination of the absolute configuration of fluoromethylated secondary alcohols by the modified Mosher method

L Xiao, T Yamazaki, T Kitazume, T Yonezawa…

Index: Xiao, Ling; Yamazaki, Takashi; Kitazume, Tomoya; Yonezawa, Tetsuo; Sakamoto, Yoshitake; Nogawa, Kouji Journal of Fluorine Chemistry, 1997 , vol. 84, # 1 p. 19 - 23

Full Text: HTML

Citation Number: 14

Abstract

Application of the modified Mosher method using high-field FT 1H NMR to the 2-methoxy-2- phenyl-2-trifluoromethyl acetic acid (MTPA) derivatives of fluorinated secondary alcohols indicates that this method may be generally used to determine the absolute configurations of these materials.

Related Articles:

Réactions de Wittig et d'Horner-Emmons en série trifluorométhylée: synthèse de nouveaux F-alkyl esters isomères α, β et β, γ-insaturés

[Trabelsi, Hedi; Bertaina, Brigitte; Cambon, Aime Canadian Journal of Chemistry, 1985 , vol. 63, p. 426 - 431]

Acid catalyzed hydration of. alpha.-cyano and. alpha.-(trifluoromethyl) vinyl ethers. Additivity of strongly activating and strongly deactivating substituent effects

[Allen, Annette D.; Shahidi,, Fereidoon; Tidwell, Thomas T. Journal of the American Chemical Society, 1982 , vol. 104, # 9 p. 2516 - 2518]

Interaction of Organolithium Compounds and Salts of Carboxylic Acids

[Bluhm et al. Journal of the American Chemical Society, 1955 , vol. 77, p. 4406]

Interaction of Organolithium Compounds and Salts of Carboxylic Acids

[Bluhm et al. Journal of the American Chemical Society, 1955 , vol. 77, p. 4406]

Interaction of Organolithium Compounds and Salts of Carboxylic Acids

[Bluhm et al. Journal of the American Chemical Society, 1955 , vol. 77, p. 4406]

More Articles...