The gomberg??bachmann reaction of purines

TC McKenzie, SM Rolfes

Index: McKenzie, Thomas C.; Rolfes, Steven M. Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 859 - 861

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Citation Number: 21

Abstract

Abstract The reaction of adenine derivatives with isoamyl nitrite in anisole solution was re- investigated. The arylated products are a mixture of ortho, meta, and para-methoxyphenyl isomers with the ortho predominating. It is concluded that this is a typical free-radical arylation and that the 6-purinyl radical is a normal, well behaved aromatic radical.