Trialkylamine-mediated intramolecular acylation of akenes with carboxylic acid chlorides

…, T Hoshikawa, S Sasaki, H Ishibashi

Index: Matsuo, Jun-Ichi; Hoshikawa, Takaya; Sasaki, Shun; Ishibashi, Hiroyuki Chemical and Pharmaceutical Bulletin, 2010 , vol. 58, # 4 p. 591 - 592

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Abstract

Trialkylamine-mediated intramolecular cyclization of pent-4-enoyl chlorides was studied. Substitution with a tertiary alkyl group at the 2-position gave cyclopent-2-en-1-ones, while substitution with an aromatic group gave enol esters, which were formed by O-acylation of initially formed 3-chlorocyclopentanones with ketenes.

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