Journal of heterocyclic chemistry

Synthesis of 3??aryl??6H??isoxazolo [3, 4??d] pyrazolo [3, 4??b] pyridines and 3??aryl??6H??isoxazolo [5, 4??d] pyrazolo [3, 4??b] pyridines

GM Shutske, FP Huger

Index: Shutske, Gregory M.; Huger, Francis P. Journal of Heterocyclic Chemistry, 1988 , vol. 25, # 2 p. 703 - 709

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Citation Number: 6

Abstract

Abstract The synthesis and characterization of a number of 3-aryl-6H-isoxazolo [3, 4-d] pyrazolo [3, 4-b] pyridines and 3-aryl-6H-isoxazolo [5, 4-d] pyrazolo [3, 4–6] pyridines from common precursors, 5-benzoyl-4-chloro-1H-pyrazolo-[3, 4-b] pyridines, has been described. The structures were determined by unambiguous chemical synthesis and by isolation and 13 C nmr analysis of some key, isolated, intermediates. The ability of these compounds to ...