Monatshefte für Chemie-Chemical Monthly

Synthesis and biological activity of 3-substituted isoxazolecarboxamides

M Gucma, WM Gołębiewski

Index: Gucma, Miroslaw; Golebiewski, W. Marek Monatshefte fur Chemie, 2010 , vol. 141, # 4 p. 461 - 469

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Citation Number: 10

Abstract

Abstract A series of novel 3-substituted isoxazolecarboxamides have been prepared. A key step was 1, 3-dipolar cycloaddition of nitrile oxides to α, β-unsaturated esters. Some of these compounds exhibited high fungicidal activities against Alternaria alternata, Botrytis cinerea, Rhizoctonia solani, Fusarium culmorum, and Phytophthora cactorum. Graphical abstract