Molecular Crystals and Liquid Crystals

Reaction Anisotropy of 2-Amino-5-(4-Fluorophenil)-1, 3, 4-Oxadiazole Crystals in Acetylation Reactions

VA Dymshits, OG Rublewa

Index: Dymshits; Rublewa Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals, 1996 , vol. 275, p. 261 - 270

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Abstract

Abstract 2-amino-5-(4-fluorophenyl)-1, 3, 4-oxadiazole (1) is a compound of ambident reactivity. Its solid-state acetylation by acetyl bromide vapours results in two monoacetyl derivatives and two diacetyl derivatives. Their structures were confirmed by UV spectra, mass spectra and thin layer chromatography data. The solid-state acetylation of compound (1) is an anisotropic reaction and the different products are formed on different crystal ...

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