Benzoylurea derivatives as a novel class of antimitotic agents: synthesis, anticancer activity, and structure− activity relationships

DQ Song, Y Wang, LZ Wu, P Yang…

Index: Okada; Koyanagi; Yamada; Haga Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 9 p. 2308 - 2315

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Citation Number: 22

Abstract

... 14b inhibited human hepatocarcinoma by 86% in volume in nude mice. ... cancer chemotherapy.( 7) Therefore, searching for drugable small tubulin ligands with novel chemical structures or ... modes of action has become an active field of investigation in medicinal chemistry.(8, 9 ...