Journal of Molecular Structure

Chiral isothiocyanates–An approach to determination of the absolute configuration using circular dichroism measurement

O Michalski, D Cież

Index: Michalski, Oskar; Ciez, Dariusz Journal of Molecular Structure, 2013 , vol. 1037, p. 225 - 235

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Citation Number: 1

Abstract

Chiral alkyl 2-isothiocyanates have been obtained from enantiopure, aliphatic amines. ECD measurements allowed us to correlate an absolute configuration at C-2 with a sign of the Cotton effect (CE) observed for n–π* transition at the longer-wavelength range of the spectrum. Chirooptical data calculated for all enantiomers were consistent with the measured CE values and indicated that the weak absorption band at 240nm could give an ...