Condensation of 2-Pyridylmethyllithium Nucleophiles and Pyridine Electrophiles as a Convenient Synthetic Route to Polydentate Chelating N-Donor Ligands

N Vedernikov, R Miftakhov, SV Borisoglebski…

Index: Vedernikov; Miftakhov; Borisoglebski; Caulton; Solomonov Chemistry of Heterocyclic Compounds, 2002 , vol. 38, # 4 p. 406 - 416

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Abstract

Abstract Condensation of 2-pyridylmethyllithium or (6-methyl-2-pyridyl) methyllithium nucleophiles and pyridine, 2-picoline, or 4-tert-butylpyridine as electrophiles leads to new polydentate N-donor ligands, methyl-, tert-butyl-substituted tripyridinedimethanes, or to tripyridinedimethane itself, in good or high yields. Depending on the reagent ratio, solvent used, and reaction conditions, the corresponding intermediate dipyridinemethanes can be ...

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