Tetrahedron Letters

A modified Curtius reaction: an efficient and simple method for direct isolation of free amine

B Ma, WC Lee

Index: Tetrahedron Letters, , vol. 51, # 2 p. 385 - 386

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Citation Number: 17

Abstract

... Tetrahedron Letters. ... 8. In this Letter, we now report a very simple modification of Curtius reaction by quenching the isocyanate intermediates (3) with sodium trimethylsilanolate (NaOTMS), which provides an efficient one-pot method for direct isolation of ... Tetrahedron, 60 (2004), pp ...

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