Enantioselective esterifications of unsaturated alcohols mediated by a lipase prepared from Pseudomonas sp

K Burgess, LD Jennings

Index: Burgess, Kevin; Jennings, Lee D. Journal of the American Chemical Society, 1991 , vol. 113, # 16 p. 6129 - 6139

Full Text: HTML

Citation Number: 332

Abstract

Abstract: Competition experiments and measurements of enantioselectivities were used to develop a simple active-site model (Figure 1) for resolutions of 8-hydroxy-a-methylene carbonyl compounds 111 via acyl transfers mediated by lipase from Pseudomonas sp.(AK). Further experiments were used to test and refine this model with respect to resolutions of allylic, propargylic, homopropargylic, and other alcohols (Tables I-IV, respectively). The ...

Related Articles:

Lipase-catalysed kinetic resolutions of secondary alcohols in pressurised liquid hydrofluorocarbons

[Ball, Anthony J.; Corr, Stuart; Micklefield, Jason Tetrahedron Letters, 2009 , vol. 50, # 26 p. 3543 - 3546]

Organoboron compounds in organic synthesis. 2. asymmetric reduction of dialkyl ketones with (r, r)-or (s, s)-2, 5-dimethylborolane

[Imai, Toshiro; Tamura, Tadashi; Yamamuro, Akira; Sato, Tsuneo; Wollmann, Theodor A.; et al. Journal of the American Chemical Society, 1986 , vol. 108, # 23 p. 7402 - 7404]

Synthesis of Four Stereoisomers of (S)??2??Methylpent??3??yl 3, 13??Dimethylpentadecanoate, a Sex Pheromone of the Bagworm Moth Clania variegate, Using …

[Taguri, Tomonori; Yamamoto, Masanobu; Fujii, Toru; Muraki, Yuta; Ando, Tetsu European Journal of Organic Chemistry, 2013 , # 30 p. 6924 - 6933]

Catalytic enantioselective addition of organoaluminum reagents to aldehydes

[Tetrahedron Asymmetry, , vol. 23, # 10 p. 789 - 794]

An organo-catalytic approach to the enantioselective synthesis of (R)-selegiline

[Talluri, Siva Kumar; Sudalai, Arumugam Tetrahedron, 2007 , vol. 63, # 39 p. 9758 - 9763]

More Articles...