Folding and self-assembling with β-oligomers based on (1R, 2S)-2-aminocyclobutane-1-carboxylic acid

…, I Díez-Pérez, S Dannenberg, S Izquierdo…

Index: Torres, Elisabeth; Gorrea, Esther; Burusco, Kepa K.; Da Silva, Eric; Nolis, Pau; Rua, Federico; Boussert, Stephanie; Diez-Perez, Ismael; Dannenberg, Samantha; Izquierdo, Sandra; Giralt, Ernest; Jaime, Carlos; Branchadell, Vicen; Ortuno, Rosa M. Organic and Biomolecular Chemistry, 2010 , vol. 8, # 3 p. 564 - 575

Full Text: HTML

Citation Number: 48

Abstract

Improved methodologies are provided to synthesize (1R, 2S)-2-aminocyclobutane-1- carboxylic acid derivatives and their incorporation into β-peptides of 2–8 residues bearing different N-protecting groups. The conformational analysis of these oligomers has been carried out by using experimental techniques along with theoretical calculations. This study shows that these oligomers adopt preferentially a strand-type conformation in solution ...

Related Articles:

Nonaromatization reactions of bicyclo [2.2. 0] hexa-2, 5-diene (Dewar benzene)

[van Tamelen,E.E.; Carty,D. Journal of the American Chemical Society, 1971 , vol. 93, # 23 p. 6102 - 6110]

Stereospecific photodimerization of unsaturated compounds induced by nickel complexes.

[Miyashita, Akira; Ikezu, Shohgo; Nohira, Hiroyuki Chemistry Letters, 1985 , p. 1235 - 1238]

Stereoselective synthesis of (−)-(1R, 2S)-2-aminocyclobutane-1-carboxylic acid, a conformationally constrained β-amino acid

[Martin-Vila, Marta; Minguillon, Cristina; Ortuno, Rosa M. Tetrahedron Asymmetry, 1998 , vol. 9, # 24 p. 4291 - 4294]

Biochemical investigation of pikromycin biosynthesis employing native penta-and hexaketide chain elongation intermediates

[Mohr, Peter; Waespe-Sarcevic, Nada; Tamm, Christoph; Gawronska, Krystyna; Gawronsky, Jacek K. Helvetica Chimica Acta, 1983 , vol. 66, # 8 p. 2501 - 2511]

Thermische Umlagerung von Bicyclo [6.1. 0] nonadien??(2.4); eine reversible, intramolekulare En??Reaktion

[Roth,W.R. Justus Liebigs Annalen der Chemie, 1964 , vol. 671, p. 10 - 25]

More Articles...