Synthesis of Arylpropylamines. I. From Allyl Chloride1

TM Patrick Jr, ET McBee, HB Hass

Index: Patrick; McBee; Hass Journal of the American Chemical Society, 1946 , vol. 68, p. 1009

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Citation Number: 12

Abstract

The isolation and proof of structure of the hormone epinephrine (generally attributed to Abela) has led in succeeding years to the synthesis of many similar compounds which have the common property of increasing the blood pressure, but may also exhibit other varied and interesting physiological effects. Inasmuch as benzedrine, l-phenyl-2-propylamine2 and its derivatives wi? re found to be among the most important of the pressor amines, 4 this ...