Tetrahedron letters

Radical aromatic substitution via atom-transfer addition

JH Byers, JE Campbell, FH Knapp, JG Thissell

Index: Byers, Jeffrey H.; Campbell, John E.; Knapp, Faith H.; Thissell, Jameson G. Tetrahedron Letters, 1999 , vol. 40, # 14 p. 2677 - 2680

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Citation Number: 28

Abstract

New methodology for radical aromatic substitution has been developed involving the addition of electron-deficient radicals to unprotected pyrroles and indole. This non-oxidative process is presumed to be occurring via atom-transfer addition of suitable organoiodides and bromides with subsequent non-radical elimination of HI or HBr, respectively. The process also occurs under stannane-free conditions.

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