Synthesis of branched heptaglycerol bearing eight hydroxyl groups with four cyclic protecting groups

H Nemoto, M Kamiya, Y Minami, T Araki, T Kawamura

Index: Nemoto, Hisao; Kamiya, Masaki; Minami, Yuki; Araki, Takaaki; Kawamura, Tomoyuki Synlett, 2007 , # 13 p. 2091 - 2095

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Citation Number: 7

Abstract

The glyceryl unit is one of the simplest trifunctionalized molecules. The preparation of compounds bearing a single glyceryl unit at each dendrimeric terminus such as 1 has been reported 2 (Figure [1] ). In contrast, compounds such as 2, which bear repetitive branched glyceryl (BGL) units, have not been reported except in our previous papers dealing with BGL. [3] It is often difficult to create ether linkage in high yield (especially at sterically hindered positions) since the alkoxy ...