Palladium-catalyzed direct arylation of azine and azole N-oxides: Reaction development, scope and applications in synthesis

…, M Bertrand-Laperle, E Villemure…

Index: Stuart, David R.; Villemure, Elisia; Fagnou, Keith Journal of the American Chemical Society, 2007 , vol. 129, # 40 p. 12072 - 12073

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Citation Number: 277

Abstract

Palladium-catalyzed direct arylation reactions are described with a broad range of azine and azole N-oxides. In addition to aspects of functional group compatibility, issues of regioselectivity have been explored when nonsymmetrical azine N-oxides are used. In these cases, both the choice of ligand and the nature of the azine substituents play important roles in determining the regioisomeric distribution. When azole N-oxides are employed, ...