Tetrahedron

Synthesis of α, β-unsaturated sulphonates via the Wittig-Horner reaction

JC Carretero, M Demillequand, L Ghosez

Index: Carretero, Juan Carlos; Demillequand, Marc; Ghosez, Leon Tetrahedron, 1987 , vol. 43, # 21 p. 5125 - 5134

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Citation Number: 47

Abstract

A general and practical method of synthesis of α, β-unsaturated sulphonates (25 examples) by the Wittig-Horner reaction is described. Reactions with the salts 2 and carbonyl compounds are not very stereoselective. On the contrary, reactions with esters 1 gave high yields of (E)-α, β-unsaturated sulphonic esters.