Tetrahedron: Asymmetry

Conversion of homochiral amines and α-amino esters to their chiral 1, 2, 3, 5-substituted pyrrole derivatives via gold-catalysed amination/annulation reactions of 2- …

A Arcadi, S Di Giuseppe, F Marinelli, E Rossi

Index: Arcadi, Antonio; Di Giuseppe, Sabrina; Marinelli, Fabio; Rossi, Elisabetta Advanced Synthesis and Catalysis, 2001 , vol. 343, # 5 p. 443 - 446

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Citation Number: 70

Abstract

Pyrrole derivatives represent a class of heterocycles of great importance because they very frequently display biological activity and are also versatile building blocks in organic synthesis. 1 Although many efficient syntheses of pyrroles have been reported, developing new synthetic methods remains an attractive goal. 2., , , , , , and Special attention is devoted to the asymmetric synthesis of heterocyclic compounds due to the enantiospecificity shown by most biological ...

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