Chemical reduction of zoalene to ANOT for use in zoalene residue studies

GK Webster, RJ Pastore, KA Hawkins…

Index: Webster, Gregory K.; Pastore, Richard J.; Hawkins, Kenneth A.; Hirsch, Arnold L. Journal of Agricultural and Food Chemistry, 1998 , vol. 46, # 9 p. 3623 - 3629

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Citation Number: 4

Abstract

A novel chemical synthesis and purification scheme to produce ANOT (3-amino-5-nitro-o- toluamide) was developed to yield an analytical standard grade material for zoalene residue investigations. An original conversion of zoalene (3, 5-dinitro-o-toluamide) to ANOT was developed. Several literature references were available for the partial reduction of dinitro aryl compounds, but none detailed the conversion of zoalene to ANOT. A chemical ...