α-Oxygenated Pyridines. IV. The Synthesis of an Isomer of Pyridoxamine1, 2

RP Mariella, EP Belcher

Index: Mariella; Belcher Journal of the American Chemical Society, 1952 , vol. 74, p. 4049

Full Text: HTML

Citation Number: 4

Abstract

Methyl Methoxyacetate. Method A.-A solution of 374 g. of chloroacetic acid in 200 ml. of methanol containing 50 ml. of concentrated sulfuric acid was refluxed for six hours. The solution was neutralized with a saturated solution of sodium bicarbonate, filtered, and the aqueous layer ex-tracted with ether. The dried ether extract was distilled. The methyl chloroacetate boiled at 126-130', 304.8 g.(717, yield).

The synthesis of some isomeric dimethyl-hydroxymethylpyridines. 3, 4-Didesoxypyridoxin

[Mariella; Leech Journal of the American Chemical Society, 1949 , vol. 71, p. 331]

Reductive desulfurization of 3-cyano-2-methylthiopyridines under the action of Raney nickel

[Zubarev; Zav'yalova; Litvinov Russian Chemical Bulletin, 2005 , vol. 54, # 11 p. 2578 - 2581]