Kinetics of the pyridoxal-catalyzed dealdolation and. beta. elimination of some aromatic. beta.-hydroxy. alpha.-amino acids

JA Marcello, AE Martell

Index: Marcello, Joseph; Martell, Arthur E. Journal of the American Chemical Society, 1982 , vol. 104, # 12 p. 3441 - 3447

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Citation Number: 4

Abstract

Abstract: The rates of dealdolation and@ elimination of a number of para-substituted phenylserines have been determined by proton NMR. Electron-withdrawing substituents on the amino acid side chain enhance the dealdolation rate. In the substituted phenylserines/3 elimination and dealdolation were found to occur as parallel reactions. The metal ion- pyridroxal catalyzed systems undergo reaction more rapidly than the metal-free pyridoxal- ...

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