Water??Soluble, Donor–Acceptor Biphenyl Derivatives in the 2??(o??Nitrophenyl) propyl Series: Highly Efficient Two??Photon Uncaging of the Neurotransmitter γ?? …

…, CM Davenport, C Herbivo, D Warther…

Index: Donato, Loic; Mourot, Alexandre; Davenport, Christopher M.; Herbivo, Cyril; Warther, David; Leonard, Jeremie; Bolze, Frederic; Nicoud, Jean-Francois; Kramer, Richard H.; Goeldner, Maurice; Specht, Alexandre Angewandte Chemie - International Edition, 2012 , vol. 51, # 8 p. 1840 - 1843

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Citation Number: 63

Abstract

By using two-photon (TP)[1] photoreleasable neurotransmitters like glutamate (Glu) or g- aminobutyric acid (GABA), neuronal processes can be activated or inhibited with high temporal and spatial control (with around one micron threedimensional precision) with reduced photodamage to cells or organs, and with deeper penetration of the light beam into living tissue compared to that of UV photoactivation.[2] Whereas TP excitation of ...