The Journal of Organic Chemistry

Intramolecular Migration of the Pentafluorophenyl Group under Acidic Conditions

R Filler, Y Rao

Index: Filler,R.; Rao,Y.S. Journal of Organic Chemistry, 1974 , vol. 39, p. 3421 - 3423

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Citation Number: 6

Abstract

Acid-catalyzed skeletal rearrangements involving the 1, 2 shift of aryl groups are well known. Phenyl groups containing electron-attracting substituents generally migrate much more slowly than phenyl, if at all. One might anticipate that the moderately electron-withdrawing pentafluorophenyl group2a would cause considerable deactivation in such reactions. To our knowledge, acid-catalyzed rearrangements involving intramolecular 1, 2 migration of the ...

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