Asymmetric synthesis catalyzed by chiral ferrocenylphosphine-transition metal complexes. 2. Nickel-and palladium-catalyzed asymmetric Grignard cross-coupling

T Hayashi, M Konishi, M Fukushima…

Index: Hayashi, Tamio; Konishi, Mitsuo; Fukushima, Motoo; Mise, Takaya; Kagotani, Masahiro; et al. Journal of the American Chemical Society, 1982 , vol. 104, # 1 p. 180 - 186

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Citation Number: 249

Abstract

Abstract: Various kinds of chiral ferrocenylphosphines, which have both planar and central elements of chirality and also a functional group on the side chain, have been used as ligands for nickel or palladium complex catalyzed asymmetric cross-coupling of secondary alkyl (1-phenylethyl, 2-octy1, and 2-butyl) Grignard reagents with organic halides such as vinyl bromide,(E)-8-bromostyrene, 2-bromopropene, and bromobenzene.(9-NJ-Dimethyl- ...