The Journal of organic chemistry

A General Procedure for the Preparation of β-Ketophosphonates

KM Maloney, JYL Chung

Index: Maloney, Kevin M.; Chung, John Y. L. Journal of Organic Chemistry, 2009 , vol. 74, # 19 p. 7574 - 7576

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Citation Number: 45

Abstract

A mild, high-yielding procedure for the preparation of β-ketophosphonates is described. The condensation is general with respect to the ester and phosphonate, and the products are obtained in high yields within minutes at 0° C. The reaction procedure is operationally simple and amenable to large-scale preparations.

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