Convenient route for the synthesis of 3-substituted and 3, 4-disubstituted pyrrole-2, 5-dicarbaldehydes

S Cadamuro, I Degani, R Fochi, A Gatti…

Index: Cadamuro, Silvano; Degani, Iacopo; Fochi, Rita; Gatti, Antonella; Piscopo, Laura Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 19 p. 2365 - 2369

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Citation Number: 6

Abstract

3-Substituted and 3, 4-disubstituted pyrrole-2, 5-dicarbaldehydes have been obtained by hydrolysis with HgO–35% aq. HBF–DMSO of the intermediates 4 and 5 prepared by electrophilic substitution reactions on 2, 5-bis (1, 3-benzodithiol-2-yl) pyrrole. The overall yields starting from pyrrole ranged from 41–88%.

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