The aza–ene or the Michael addition? Examination of an unusual substituent effect on the reaction of heterocyclic ketene aminals with ethyl propiolate

MX Zhao, MX Wang, ZT Huang

Index: Zhao, Mei-Xin; Wang, Mei-Xiang; Huang, Zhi-Tang Tetrahedron, 2002 , vol. 58, # 7 p. 1309 - 1316

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Citation Number: 41

Abstract

Heterocyclic ketene aminals having at least one secondary amino group underwent the aza– ene reaction with ethyl propiolate under various conditions to yield the corresponding adducts, which were readily transformed into the δ-lactam fused heterocyclic products with ...