Isotopic effect study of propofol deuteration on the metabolism, activity, and toxicity of the anesthetic

J Helfenbein, C Lartigue, E Noirault…

Index: Journal of Medicinal Chemistry, , vol. 45, # 26 p. 5806 - 5808

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Citation Number: 32

Abstract

... Journal of Medicinal Chemistry. ... Indeed, it may induce some modifications of the chemical and physicochemical properties of the labeled drugs (polarity, molar volume, electron donation, van der Waals forces, dipolar moment, and lipophilicity) and therefore may contribute to ...

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