Enantioselective oxidative-coupling of polycyclic phenols

S Takizawa, J Kodera, Y Yoshida, M Sako, S Breukers…

Index: Takizawa, Shinobu; Kodera, Junpei; Yoshida, Yasushi; Sako, Makoto; Breukers, Stefanie; Enders, Dieter; Sasai, Hiroaki Tetrahedron, 2014 , vol. 70, # 9 p. 1786 - 1793

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Citation Number: 10

Abstract

Abstract Enantioselective oxidative-coupling of polycyclic phenols, such as 2-anthracenol, 9- or 3-phenanthrol, and 5-chrysenol was established by using vanadium (V/IV) catalysis under air or O 2 as a co-oxidant. In the vanadium catalyzed reaction, the corresponding coupling products were obtained in good to excellent yields with up to 93% enantiomeric excess.