Magnetic resonance in chemistry

Use of NOE difference spectra to determine configurations and conformations of imidate esters

DE Gallis, DR Crist

Index: Gallis, David E.; Crist, DeLanson R. Magnetic Resonance in Chemistry, 1987 , vol. 25, p. 480 - 483

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Citation Number: 3

Abstract

Abstract A new method for determining conformations and configurations of imidate esters was developed based on NOE difference spectra in CDCI 3. As a test of the method, methyl N-methylacetimidate was determined to exist in the E configuration, ap conformation, in agreement with assignments by homoallylic coupling and dipole moment data. Methyl N-tert- butylformimidate, for which existing methods were not suitable, was also determined to ...