Facile synthesis of ethyl 3, 3-difluoroacrylate from dibromodifluoromethane and Diels-Alder cycloaddition with furan

J Leroy, H Molines, C Wakselman

Index: Leroy, Jacques; Molines, Huguette; Wakselman, Claude Journal of Organic Chemistry, 1987 , vol. 52, # 2 p. 290 - 292

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Citation Number: 55

Abstract

Esters of acrylic acid have received continuous interest as reagents in organic synthesis. On the contrary, their &fluorinated analogues were somewhat deserted, 2 albeit they potentially allow the direct introduction of one or several fluorine atoms into a molecule. Thus, for an attempted route to 6, 6-difluoroshikimic acid, we needed esters of 3, 3-difluoroacrylic acid (1). Previously, such