Tetrahedron

Cu (I)-mediated lactone formation in subcritical water: a benign synthesis of benzopyranones and urolithins A–C

P Nealmongkol, K Tangdenpaisal, S Sitthimonchai…

Index: Nealmongkol, Prattya; Tangdenpaisal, Kassrin; Sitthimonchai, Somkid; Ruchirawat, Somsak; Thasana, Nopporn Tetrahedron, 2013 , vol. 69, # 44 p. 9277 - 9283

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Citation Number: 17

Abstract

Abstract Benzopyranones were successfully synthesized using Cu (I)-mediated C–O bond formation in subcritical water. A number of benzopyranone derivatives including polymethoxy benzopyranones, benzopyranopyridones, chromenoindolones, and furochromenones were synthesized in satisfactory yield. This methodology was further applied to synthesize the intestinal microbial metabolites, urolithins A, B, and C, which ...

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