Scope of tandem cycloadditon/radical cyclization methodology

T Ghosh, H Hart

Index: Ghosh, Tirthankar; Hart, Harold Journal of Organic Chemistry, 1989 , vol. 54, # 21 p. 5073 - 5085

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Citation Number: 19

Abstract

Tandem cycloaddition/radical cyclization is an effective strategy for the rapid assembly of a wide variety of ring systems. To set up the reagents for this sequence, it is necessary to include a potential radical site in one of the two cycloaddition partners, located at an appropriate distance from a new double bond that will be formed in the cycloaddition step. Examples in which the cycloaddition step is [4+ 21 or [3+ 21 and in which the radical ...