Synthesis and antifungal action of new tricyclazole analogues

…, C Romagnoli, E Andreotti, M Manfrini…

Index: Mares, Donatella; Romagnoli, Carlo; Andreotti, Elisa; Manfrini, Maurizio; Vicentini, Chiara Beatrice Journal of Agricultural and Food Chemistry, 2004 , vol. 52, # 7 p. 2003 - 2009

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Citation Number: 31

Abstract

Melanins are very important pigments for the survival and longevity of fungi, so their biosynthesis inhibition is a new biochemical target aiming at the discovery of selective fungicides. In this work is described the synthesis of new pyrazolo-thiazolo-triazole compounds, analogues of tricyclazole (a commercial antifungal product that acts by inhibiting melanin synthesis), and their biological activity was studied on some ...